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The FDA does not approve supplements to diagnose, treat, prevent, or cure diseases

Additionally, sermorelin raises cortisol and blood pressure in some individuals, which could amplify tirzepatide's cardiovascular effects if not offset by weight loss benefits

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CYP2A6 is the main enzyme involved in metabolising nicotine, the anticancer drug 5-fluorouracil, and various prescription drugs (106)

The results are often cumulative, and regular infusions may be needed to sustain the benefits over time