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Tirzepatide carries a boxed warning regarding the risk of thyroid C-cell tumors, based on animal studies, though the relevance to humans remains uncertain

The cold chain refers to the uninterrupted series of temperature-controlled storage and distribution activities

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Two subcutaneous fixed-ratio combinations of basal insulin and GLP-1 RA are currently available for once-daily administration: insulin degludec/liraglutide (IDegLira) and insulin glargine/lixisenatide (IGlarLixi) [5]