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ETD of -2.94%), but the overall magnitude of weight loss was still less than what was reported in the STEP and SUSTAIN trials, where average weight reductions reached ranges of 5-15% (ETD of -2.6% to -12.5%) over a similar duration of treatment with high-dose GLP-1s
Liraglutide (Saxenda), an earlier GLP1 medication, uses a similar approach but has a shorter half-life of about 13 hours, requiring daily injection
Journal of Dermatological Science, 94(3), 135-142
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For the second experiment (Fasting study): Mice were sacrificed after 16 h of fasting, and livers were collected and snap-frozen in liquid nitrogen until further processing
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