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The interaction between the gut immune barrier and these microbes contributes to the GI tract becoming a potential source of chronic inflammation, which is closely associated with gut microecology (174, 175)

Low incidences of seizures have been reported with oral doses in individuals with or without pre-existing seizure disorders

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Modalities span checkpoint inhibitors, ADCs, CAR-T and targeted small molecules, with pipelines in protein degraders and bispecifics

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