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Recently, as a method to ensure proper synchronization of the PE and peptide, and to prevent dilution, the development of formulations capable of uni-directional release, i.e., gastrointestinal patches [148,149] and microcontainers [150,151], is emerging

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Endocrine 47 , 107116 (2014)

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This peptide-pathway genetic assessment maps 14 pathways and 49 peptidesincluding variants in GLP1R (rs6923761), GIPR (rs1800437), FTO (rs9939609), and MC4R (rs17782313)to reveal personalized predispositions that inform treatment optimization and long-term strategy