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Yes, certain medications promote weight gain and can counteract GLP-1 effects, including antipsychotics (olanzapine, clozapine), mood stabilizers (valproate, lithium), some antidepressants (mirtazapine, paroxetine), corticosteroids, and diabetes medications like insulin or sulfonylureas

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insulin is a peptide) or available as a supplement or medication (e.g

Works alongside keto, paleo, intermittent fasting, or Mediterranean eating

In experimental models with hepatic steatosis induced by a fat-rich diet, a diminution was found of transcription due to the diminished levels of mRNA of the components AMPK-PGC-1, NRF-2, and -ATP synthase [52]

FDA-approved medications like Wegovy and Zepbound have undergone full FDA review for safety, effectiveness, and manufacturing quality