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2 Materials and methods 2.1 Animals All procedures were conducted in accordance with the Directive 2010/63/EU of the European Parliament and of the Council on the protection of animals used for scientific purposes (22.09.2010)

This material is not intended for human or animal use, and it is not a drug, supplement, diagnostic, or therapeutic product

Genome Biology

CJC-1295 is a synthetic analog of Growth Hormone Releasing Hormone (GHRH)

18 Unlike some other copper containing compounds like copper chloride or copper acetate, GHK-Cu has not been found to be cytotoxic or to cause irritation topically, making it an ideal option for delivery of copper into the skin

Blocking DHT GHK-Cu may help reduce the enzyme 5-alpha reductase, which converts testosterone into DHT