The incidence of severe hypoglycaemia was minimal and generally comparable to placebo, reflecting the glucose-dependent mechanism of GLP-1 RAs and contrasting with the higher risk of hypoglycaemia associated with insulin and sulfonylureas
Similarly, Gastaldelli et al
In rats, it may be activated by peripheral signals, such as distension of the stomach that activate the GLP-1expressing neurons of the NTS, 28 and it has also been associated with enteroceptive stress
doi: 10.1210/endocr/bqaa192 48
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