Psychiatry 28 , 7586 (2020)
Patients with inflammatory conditions may go on steroids during a flare up, and then need time to taper off later on or risk withdrawal symptoms like fatigue, body aches and nausea
While the GIPR agonism of tirzepatide likely augments the weight loss effect of GLP-1R activation, GIPR signaling may also contribute to antiinflammatory responses through direct actions on GIPR-expressing immune cells
For prolonged use, periodic monitoring of fat-soluble vitamin levels is prudent, especially if symptoms like fatigue or hair loss appear
When siRNAs of CPT-1/2 and CACT were treated, CrAT activity was significantly reduced, which suggests the importance of carnitine metabolism in Godex action
Patient expectations and accountability (program orientation, pre visit checklist, patient attestation/acknowledgement)