Beavers KM, et al
Psychiatry 9:317
The injection delivers B12 directly into the bloodstream, making it the most reliable method for patients with absorption problems, pernicious anaemia, or gastrointestinal conditions affecting B12 uptake (such as Crohn's disease, coeliac disease, or following gastric surgery)
The company has multiple phase 3 clinical trials running to see how well retatrutide treats health conditions that often overlap with obesity, including knee osteoarthritis, moderate to severe obstructive sleep apnea, chronic low back pain, cardiovascular and renal outcomes, and liver disease
doi: 10.2337/db10-1338 34 SawadaNAdachiKNakamuraNMiyabeMItoMKobayashiSet al
6.5 Emerging challenges and research priorities in intervention development While current intervention strategies have demonstrated measurable benefits in reducing EED exposure, several fundamental challenges limit their broader implementation and effectiveness