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Some formulations also act on the GIP (glucose-dependent insulinotropic polypeptide) pathway

[35] The mood boost was modest but real, hinting that these drugs may touch brain circuits far beyond metabolism

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Oral semaglutide administration was continued to maintain exposure during the 10 days of ethinylestradiol and levonorgestrel pharmacokinetic sampling

This is particularly important if you also take insulin or sulfonylureas (such as gliclazide), as there may be an increased risk of hypoglycaemia during illness, especially if your food intake is reduced

It cites an observational study reporting no increased infection rates among GLP-1 users on standard oral antibiotics, though infection duration was sometimes prolonged