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[1] Novo Nordisk got it approved for type 2 diabetes back in 2017 as Ozempic, then for weight management in 2021 as Wegovy, dosed at 2.4 mg by injection once a week

In November 2023, the FDA approved Zepbound for weight management in adults with obesity

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Similar protective effects were observed in genetically enhanced transgenic mice (STZ, 1 200 mg/kg) for MT, which resulted in a 20-fold increase in MT expression and significant prevention of STZ-induced diabetes [160]

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While headaches aren't a direct side effect of Ozempic, patients may experience them due to various factors related to the medication's effects on the body