In oncology, Bristol Myers Squibbs iberdomide and mezigdomide aim to replace older myeloma therapies with next-generation oral CELMoDs
Semaglutide (Wegovy, Ozempic) aims at one receptor (GLP-1), while tirzepatide (Zepbound, Mounjaro) homes in on two (GLP-1 and GIP)
It is the foundation of several breakthrough medications that are revolutionizing the treatment of obesity and type 2 diabetes
International Journal of Obesity , 33(9), 956961
Research Overview Retatrutide is a next-generation multi-agonist peptide that engages GIP, GLP-1 and glucagon receptors simultaneously
Nader admitted to "microdosing" GLP-1s (taking less than the dosage ordinarily prescribed), but said she wouldn't stop, claiming that she was under too much pressure to stay lean