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CCL11 predominantly acts via the CCR3 receptor, which is expressed by microglia, astrocytes, and neural progenitor cells (reviewed in: 28 )
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The thymus and thyulin levels are high in youth and low in aged individuals, and this decrease in thyulin can lead to a negative feedback loop that prevents the system from overrunning, and it may be linked to low testosterone levels and immune system issues 4m30s
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