10.1016/j.ejmech.2025.117500 30 de SantanaM
employed molecular docking and ion resonance biosensors to illustrate the strong binding affinity between PDGFR- and SalB , and SalB relieves HF by inhibiting the PDGFR- signaling pathway and inducing HSC apoptosis, and inflammatory reaction of HSC (Liu et al., 2023b)
The researchers constructed a model that introduced the ALAS2 missense mutation erythroblasts derived from human cord blood, in which enhanced BACH1 expression was emerged, leading to increased susceptibility to ferroptosis (Ono et al., 2022)
The miss regulation of the GSH levels caused a disruption of the redox homeostasis and the antioxidation defense system, yielding the accumulation of ROS and lipid peroxides
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Diet plays a critical role in maintaining optimal glutathione levels