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Who must avoid it entirely in the class framing: anyone pregnant or breastfeeding, anyone with the personal/family MTC or MEN 2 history above, and anyone with prior serious hypersensitivity to a GLP-1 agonist

Summary: AOD 9604 and retatrutide are both unlicensed investigational compounds in the UK, and there is no clinical evidence or regulatory guidance supporting their combined use

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It could not comment on individual cases without proper investigation

While Ozempic belongs to the GLP-1 receptor agonist class, Jardiance is an SGLT2 inhibitor originally developed for blood sugar control

The incretin-based mechanism of action for these agents causes them to suppress glucagon in a glucose-dependent fashion while simultaneously inducing insulin secretion