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2022 AHA/ACC/HFSA guideline for the management of heart failure: a report of the American College of Cardiology/American Heart Association Joint Committee on clinical practice guidelines

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doi:10.1038/s41598-017-13587-7

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Subjects were 54 healthy adults (41 females/13 males), 28-72 years of age (mean=46.6 years)

Once your routine feels comfortable and consistent, some people may include serum in both morning and evening routines depending on personal preference