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The GLP-1 and GIP receptors play essential roles in augmenting insulin secretion and glucose homeostasis, whereas GCG receptor engagement elevates circulating GCG levels, promoting catabolic processes

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World Health Organization

GLP-1 patches, on the other hand, are unregulated herbal supplements with very limited research behind them

Notably, our previous research highlighted how individuals with T2D initiate GLP-1 RA treatment at lower A1c and BMI levels in more recent years (Cartwright et al., 2024), reflecting a trend toward broader and more accessible use of these drugs

Further longer term studies of normal and genetically modified rodents are clearly warranted