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Overexpression of the insulin-like growth factor I receptor in human colon carcinomas

however, placentally-derived compounds alleviated postmenopausal symptoms in estrogen-deprived women, and clinical case reports described premature sexual development in children using placental-derived hair products, indicating that placentally-derived materials preserve some of the native tissue estrogenic effects (Tiwary, 1998

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The mechanisms and potential therapeutic applications described remain under investigation and are not established for routine clinical use