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The skyrocketing demand for GLP-1 weight-loss medications has led to a surge in compounding pharmacies producing similar products at lower prices, but researchers warn that these medications are not always as safe as they claim
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Research on obese mice suggests that unimolecular poly-pharmacology is an effective means to deal with various mechanisms leading to obesity and further indicates that GCGR activation is the distinguishing factor between single or double agonists and triple agonists of incretin receptors (127)
Access, Cost and Shifting Landscape As people on these agents meet their weight and diabetes goals, there is concern that insurance companies will reduce or stop coverage given the high price tag of lifelong incretin therapy
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