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Glutathione is the mother of all antioxidants, the master detoxifier and maestro of the immune system Glutathione is a tripeptide made up of 3 amino acids

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When MTX enters a cell through carriers referred to as human-reduced folate carriers (SLC19A1), polyglutamate synthetase attaches glutamate residues to the -carboxylate group of MTX, converting it into methotrexate polyglutamates (MTX-PGs)

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