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At this time, they should not replace proven treatments but may have a role in carefully selected, closely monitored patients

TMA can be absorbed in the intestines and delivered to the liver through the portal circulation, where it is converted to TMAO by hepatic FMOs (Lang et al., 1998

Here's what it doesn't mean: those results came from the FDA-approved Wegovy formulation in a controlled trial setting, with a specific patient population, a specific dosing protocol, and lifestyle intervention built in

3 Beyond the U.S., obesity figures continue to rise, with almost a quarter of the global population predicted to be obese by 2035

126 (eds Zochodne, D