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For doses exceeding 1.0 mL, either split into multiple injections at different sites or use multiple vials as needed

Glucagon receptor activity, in particular, drives energy expenditure and fat oxidation in ways the GLP-1 and GIP pathways alone do not

Splitting your semaglutide injection is not recommended without explicit guidance from your provider

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Lastly, they may also not be suitable for individuals with severe kidney or liver disease

The medication received FDA approval for chronic weight management in adults with obesity on November 8, 2023 [1]