In recent years, the therapeutic footprint of this class has grown: long-acting agents (e.g., liraglutide, semaglutide) and next-generation dual/triple agonists (e.g., tirzepatide) have demonstrated superior glycemic control, weight reduction, and cardiovascular benefits in adults with T2DM (Yao et al., 2024)
Alternatively, it is possible to modulate the host immune response and alleviate UC inflammation by altering the composition of the intestinal microbiota, such as through supplementation with specific probiotics or the development of analogs of microbial metabolites
Ochoa S, Milam VT (2025) Direct Modeling of DNA and RNA Aptamers with AlphaFold 3: a promising tool for predicting aptamer structures and aptamertarget interactions
Ready, steady, go
These results reveal a gate-keeper role of APC inhibitory neurons in pain regulation, in addition to their indispensable role in mediating fear-induced analgesia
By increasing glucose uptake in muscle cells, IGF-1 helps lower blood glucose levels, thereby reducing the need for insulin secretion (Clemmons, 2004)
