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Despite this potential, given the known long-term benefit of lowering hemoglobin A1c in preventing DR progression, there does not appear to be any contraindication to initiating GLP-1/GIP agonist therapy with appropriate ocular monitoring
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Because of this, these drugs are used to treat type 2 diabetes
This metabolic shift is hypothesized to enhance mitochondrial function, reduce oxidative stress, and modulate neurotransmitter balance (Lim et al., 2022)
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