GHK-Cu is noted to cause more injection site reactions than many other peptides
80 Kuwabara, S
1 The cycle of depletion
Common B12 deficiency symptoms include fatigue, anxiety, depression, poor memory, confusion, brain fog, tingling or numbness in the extremities, zings or zapping feelings in the extremities, anemia, shortness of breath, muscle weakness, irritability, tender calves, pale complexion and more
Each individual component has been studied in preclinical models: BPC-157 (molecular weight: 1419.556 g/mol) is a synthetic fragment derived from a gastric protein, frequently examined in rodent studies on gastrointestinal integrity, vascular changes, and soft-tissue injury
While these symptoms may be reactive in some IC/BPS patients, there is also some evidence that there may be a common biologic mechanism involved