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In the current study, HPE treatment with MTX resulted in a relative amelioration in body weight changes, biochemical, ultrastructural and biophysical alterations when compared with the MTX group

This study shows the beneficial therapeutic effect of pharmacological HIF2 inhibitor belzutifan in a murine model of polycythaemia, pulmonary hypertension, pulmonary fibrosis and complications due to gain-of-function mutation of HIF2A

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