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Hepatic gene expression analysis also revealed that sterol regulatory elementbinding transcription factor 1 ( Srebf1 ) mRNA expression was significantly upregulated in HFHC-fed Dpp4 / mice but unchanged in SLD-fed mice and HFHC-fed Dpp4 hep/ mice, compared with controls (Figure 3N)

Practical guide to SHAP analysis: explaining supervised machine learning model predictions in drug development

doi: 10.1038/s43018-023-00647-3

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