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discovered that lycopene significantly decreased the incidence of AOM-induced ACF, the earliest precursor of CRC, by inhibiting of COX-2 and iNOS, which were overexpressed in the process of colorectal carcinogenesis, thereby preventing the development of CRC (49)

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She recommends consuming between 2 and 3 liters of H2O a day, which translates to about 64 to 100 ounces