566 This is also an important mechanism of AD, leading to neurological dysfunction and disease progression
Interpretation of the findings is difficult because data was only provided for the 'responder' subgroup and this did not include standard deviations or units for plasma GSH or GSH:GSSG, nor did it state whether the GSH values reported in Figure 4 of their paper represented tGSH or reduced glutathione
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Wang H, Li L, Qin LL et al (2018) Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency
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Additionally, GPxs due to their subcellular compartmentalization (cytoplasmic, membrane, ER, and mitochondrial localizations) control the local concentration gradient of peroxides and thereby regulate the activation/deactivation of redox-responsive signaling pathways [1, 8,9,10]