Semaglutide (Wegovy), tirzepatide (Zepbound), and liraglutide (Saxenda) are FDA-approved for weight loss in patients without diabetes
This regulatory context is important: both medicines sit outside standard NHS prescribing pathways for most patients, and robust safety data in real-world UK populations is limited
Three compounds, three distinct evidence bases, zero mechanistic overlap
Good sources of insoluble fiber include whole grains, nuts, and vegetables like broccoli and cauliflower
Toxicol Appl Pharmacol 193:18 Buchet JP, Lauwerys R (1985) Study of inorganic arsenic methylation by rat-liver in vitrorelevance for the interpretation of observations in man
Oxidative stress: an essential factor in the pathogenesis of gastrointestinal mucosal diseases