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Brown adipose tissueA therapeutic target in obesity

A systematic review and meta-analysis of 37 randomized controlled clinical trials with dose-response analysis concluded that carnitine supplementation:[3] achieved a modest reduction in body weight , improving Body Mass Index (BMI) and reducing adipose tissue

[4] In the SURMOUNT-1 obesity trial, a 72-week placebo-controlled study in 2,539 adults with obesity (without diabetes), mean weight change was 15.0%, 19.5%, and 20.9% at the 5, 10, and 15 mg doses versus 3.1% for placebo

Overdose of certain B vitamins can cause symptoms such as gastrointestinal upset, skin lesions, or neurological abnormalities

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