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CBD treatment (10M) for 48h led to the induction of caspase 3/7 activation (green color) of apoptotic pathways in most cells as determined by fluorescence imaging along with nuclear stain(blue)

The half-life of UA and UA-glucuronide ranges from 17 ~ 22 h, whereas the half-life of UA-sulfate is slightly longer, varying between 25 ~ 58 h (7)

doi: 10.1016/j.jare.2024.01.019 Summary Keywords hepatoprotective effect, glutathione, Ganoderma lucidum extract, vitamin C, gut microbiota, metabolomics Citation Wang Y, Zhang Y, He Y, Zhang S, Huang B, Wang Y, Lin W, Xiao W, Zou Z and Cui G (2025) GGV formula attenuates CCl 4 -induced hepatic injury in mice by modulating the gut microbiota and metabolites

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This is why the clinical picture is almost never simple