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As a controlled substance, it carries a potential for dependence with misuse, which is why it requires a prescription and cardiovascular screening before dispensing

These results suggest that NRF2 addiction in cancer cells is established only after overcoming disadvantages and liabilities accompanying the persistent transcriptional activation mediated by NRF2

Its hard to tell exactly what is happening from this dataset, so we need follow-up studies to help us understand whether the differences seen here hold up in randomized trials. It is unclear how much if any of the benefits observed among GLP-1 users in this study and prior investigations are due to an antitumor effect, but Fuemmeler outlined three potential pathways

It is one of the most impressive weight loss drugs on the market to date

It is a supportive dietary tool that works through documented hormonal pathways, not a standalone solution that replaces lifestyle factors

However, individual health conditions and medications should be reviewed to ensure safety