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However, it is unsuitable for patients with a family history of specific thyroid carcinomas or Multiple Endocrine Neoplasia syndrome type 2

Both injection and oral semaglutide can cause fatigue during the adjustment period, but injection formulations typically reach steady-state levels faster, concentrating fatigue into a shorter, more intense window

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Clinical uses: Orthostatic hypotension due to autonomic dysfunction Dialysis-induced hypotension Supportive use in cirrhosis with refractory ascites (off-label) Note: Patients are advised to avoid taking it near bedtime to reduce the risk of supine hypertension