[8] Martens CR, Denman BA, Mazzo MR, Armstrong ML, Reisdorph N, McQueen MB, Chonchol M, Seals DR
Here's something you might not know: most of the spermatozoa that leave the testes are actually infertile, 16 only becoming fertile after undergoing several biochemical processes while they cross the male and female genital tracts
Whats Next: Regulatory filing for weight management: by end of 2025 Submission for type 2 diabetes: expected in 2026 Drug discovered by Chugai, licensed by Lilly in 2018 Implication: Orforglipron could become the first once-daily oral GLP-1 therapy with potent glucose-lowering and weight-loss benefits, potentially disrupting the injectable incretin market.
Why the Scale May Not Move Right Away One of the biggest frustrations with semaglutide is feeling less hungry but not seeing immediate weight loss
The second big hypothesis, the one that is currently in vogue, is the amyloid cascade hypothesis
In a study by Takeuti et al., T2DM patients consumed 30 g of glutamine diluted in 200 ml of water for one day, and the authors observed a significant reduction in blood glucose 2 h after the ingestion of glutamine