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Recently Novo Nordisk announced the initiation of REDEFINE 4, a phase 3 trial comparing CagriSema 2.4 mg with Lillys Zepbound 15 mg evaluating weight loss after 72 weeks in 800 obese patients non-diabetic and is expected to be completed by October 2025 (NCT06131437)

Stem Cell Res Ther 6:19 Acknowledgments Not applicable

56,57 Besides these, it is well known that the AKT and p38/MAPK signaling pathways are involved in angiogenesis, and these pathways participate in multiple stages of this process