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Key Components of the Intramuscular Injection Protocol: Dosage: 1 mg of vitamin B12 per injection Frequency: Several times a week Administration: Directly into muscle tissue Clinical Evidence Showing Greater Efficacy for Severe Cases Research backs the use of high-dose B12 for severe neuropathy

In VRK2-KO cells, most of cells displayed ER distribution of SLC7A11 regardless of monensin addition or removal, suggesting that VRK2 did not have an influence on Golgi-to-PM trafficking of SLC7A11 (Fig

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