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In this system, Atg4, Atg7, and Atg3 mediate the conjugation of soluble LC3 (microtubule-associated protein 1 light chain 3) to phosphatidylethanolamine (PE), producing LC3-II
No human data exists on optimal injection site, depth, or volume
USA 90 , 347351 (1993)
Ultimately, this FOXO4-DRI-mediated mechanism selectively eliminates senescent endothelial cells, which in turn attenuates vascular inflammation and improves endothelial-dependent vasodilation, conferring a significant protective effect on vascular function
was conducted in Iran [28]