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In addition, presence of high concentrations of polyunsaturated fatty acids in the brain enhances their peroxidation and generation of toxic products which further causes degeneration of the cells harboring them or in vicinity 22

FIGURE 3 FIGURE 4 Glutathione cellular distribution Glutathione is found in almost all cellular compartments, including the nucleus (5, 54, 6468) (Figures 2, 4)

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10.1155/2015/797862 121 DupuisL.ChioA

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Which metabolites would be so important and potentially reactive