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Yes, with insulated packaging and gel packs (not ice in direct contact with vials)

In the withdrawal trial, continuing preserved loss far better than switching to placebo, which regained about 14% over a year. The metabolic benefit fades in proportion to the weight regained, so a taper plus protein and resistance training beats a hard stop

Others who might be prescribed B12 shots are those at the highest risk for a B12 deficiency, including: Vegans, since vitamin B12 is found only in animal products People ages 60 and up since their bodies don't absorb B12 as efficiently People with Crohn's disease or pancreatic disease, since they prevent nutrient absorption People who had weight-loss surgery, which decreases B12 absorption People with an eating disorder People with HIV People with diabetes Since a mild B12 deficiency might not cause symptoms, it can go undetected for years since levels are not checked during routine blood work

Consider an animal study scenario: a researcher dosing each animal at 250 mcg per kilogram of body weight, using a 1,000 mcg/mL solution

B12 injections are commonly used to boost energy levels, improve mood, support the immune system, and promote overall wellbeing

For that reason, buy your injectable B12 in dry form and keep it that way for as long as you can