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Skin texture was measured by a PRIMOS CR apparatus (anterior forearm) and tape-stripping of the SC (facial region) was analyzed for protein analysis and lipid/ceramide content using a ACQITIC UPLC system

Therapeutic relevance of GLP-1 Incretins are gut-derived peptide hormones released after nutrient ingestion that enhance glucose-dependent insulin secretion from pancreatic cells

doi: 10.1098/rstb.2006.1861 146 MountjoyKG

SURPASS PROGRAM: CLINICAL OUTCOMES Glycemic outcomes Tirzepatide reduced HbA1c in a dose-dependent manner across all the studies using both estimands (Table 2, Fig