Tamai K, Takamatsu K, Kazuki K
J Biol Chem 2000;275:40064-72 16 -Wagner CA ea
The aim is to reduce progression and to reduce the need for future knee replacement or other knee surgeries
Recommended Dosing Protocols Common bodybuilding and recovery-focused protocols include: Subcutaneous: 200500 mcg once or twice daily, near the injury site or in abdominal fat Intramuscular: 200300 mcg directly into the affected muscle, rotating sites Oral: 250500 mcg dissolved in water once daily, though bioavailability may vary Many protocols begin at the lower end, around 200 mcg, during the first week to assess tolerance
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Funding This investigation did not receive any specific grants from funding agencies in the public, commercial, or nonprofit sector