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For example, a study of MTHFR polymorphism genotypes in colorectal cancer patients reported that the frequency of methylated Bcl-2 promoter was significantly higher in individuals with CC genotype than that of those with CT and TT genotypes, and a significant difference of C and T alleles distribution were observed between patients with methylated and unmethylated Bcl-2 promoter 35

Pharmacokinetics (PK) and pharmacodynamics (PD) of RG7112, an oral murine double minute 2 (MDM2) antagonist, in patients with leukemia and solid tumor

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We observed that intracellular ferrous iron increased in activated, but not intact, B cells upon treatment with a high concentration (10 2 mM) of KI (Fig

prausnitzii to CKD mice orally lowered renal inflammation and dysfunction and reduced the serum levels of various uremic toxins