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FIGURE 1 Complex I (cI) is an NADH-ubiquinone oxidoreductase that pumps four protons into the intermembrane space (IMS) upon each NADH oxidation

We note that, for purposes of identifying significant procedure codes for examination under the 2 times rule, we consider procedure codes that have more than 1,000 single major claims or procedure codes that both have more than 99 single major claims and contribute at least 2 percent of the single major claims used to establish the APC cost to be significant (75 FR 71832)

Such supersaturations and the nature of the precipitated material are therefore investigated (Methods, 3.2.5 and 4

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