These include: Nausea (the most common complaint, particularly in the first few weeks) Vomiting Diarrhoea or constipation Decreased appetite (which, while therapeutically desirable, can occasionally be excessive) Abdominal discomfort or bloating Injection-site reactions (such as redness, itching, or mild swelling at the injection site) Headache, dizziness, and fatigue , particularly during early treatment These effects are generally dose-dependent and tend to diminish as the body adjusts to the medication
Neuropsychopharmacology 39, 22332243
GLP-1 Management for PCOS At PCOS Sisters, we provide GLP-1 treatment designed specifically for women with PCOS
Common dosing mistakes women make with retatrutide Starting and escalation errors Most protocol failures come from the same handful of errors
University of Virginia Health
Metformin and Ozempic both commonly have digestive side effects, including abdominal pain, heartburn, nausea, vomiting, diarrhea, and constipation