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When you add ibuprofen to this equation, the risk of stomach irritation increases because NSAIDs already carry a known risk of gastric ulceration and bleeding

Zrzavy, R

10.1016/j.cmet.2018.04.008 229

In a mouse model of autism spectrum disorder, treatment with indole-3-propionic acid was shown to restore impaired inhibitory synaptic transmission in the hippocampal dentate gyrus via ERK1 signaling, resulting in improved social behavior