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Gene Expression and Anti-Aging Research AHK-Cu is extensively investigated for its potential role in gene expression modulation and anti-aging pathways

Many chemicals have been reported to induce ER stress and subsequently cause toxicity in hepatic and extra-hepatic cells (Ren et al., 2016

Pharmacol Res-Modern Chin Med (2021) 1:100011

It can attenuate CoI, -SMA, and endogenous TGF-1 production and inflammatory processes while inhibiting TGF-1-induced proliferation, differentiation, and fibroblast-to-myofibroblast transformation in PF (Zhang et al., 2014

Indeed, both TNF- and IL-1 can stimulate ROS production and inhibit mitochondrial respiration, whilst increasing glycolytic activity and lactate production (199)

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