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First, all data involved in the analysis are derived from individuals of European ancestry, which limits the generalizability of the MR study results to other ethnic groups

The medication is administered as a once-weekly subcutaneous injection and works through several mechanisms

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With a half-life of 6 to 8 days, meaningful blood levels persist for approximately 3 to 4 weeks after the last injection

[DOI] [PubMed] [Google Scholar] 32.Wang N, Tan HY, Li S, et al

Similarly, the aging rats untreated with IGF1 exhibit a significant mitochondrial dysfunction, including reduced activity of ATPase and complex IV (Garcia-Fernandez et al., 2008