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Diuretics and forced diuresis should be avoided

Credelio (lotilaner) Indications: Credelio kills adult fleas and is indicated for the treatment and prevention of flea infestations and treatment and control of tick infestations (lone star tick, American dog tick, black-legged tick, and brown dog tick) for one month in dogs and puppies 8 weeks and older and 4.4 pounds or greater

31 The rate of revision and rate of failure was not statistically significant although including one additional study by Trams et al

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It is not a single-pathway molecule

Short-term side effects were not observed in this small population, and they did not evaluate if it actually worked for a specific condition or if it was safe for long-term use. Jamie Richardson, BVetMed, head of veterinary medicine at Small Door Veterinary, shares the same concerns